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(n.) A ban or curse pronounced with religious solemnity by ecclesiastical authority, and accompanied by excommunication. Hence: Denunciation of anything as accursed.
(n.) An imprecation; a curse; a malediction.
(n.) Any person or thing anathematized, or cursed by ecclesiastical authority.
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Webster, Noah. Entry for 'Anathema'. Noah Webster's American Dictionary. https://www.studylight.org/dictionaries/eng/web/a/anathema.html. 1828.