VI. was the son of Bohemund V. by Luciana, a daughter of the count of Segni, nephew of Innocent III. Born in 1237, Bohemund VI. succeeded his father in 1251, and was knighted by St Louis in 1252. His sister Plaisance had married in 1250 Henry I. of Cyprus, the son of Hugh I.; and the Cypriot connexion of Antioch, originally formed by the marriage of Bohemund V. and Alice, the widow of Hugh I., was thus maintained. In 1252 Bohemund VI. established himself in Antioch, leaving Tripoli to itself, and in 12J7 he procured the recognition of his nephew, Hugh II., the son of Henry I. by Plaisance, as king of Jerusalem. He allied himself to the Mongols against the advance of the Egyptian sultan; but in 1268 he lost Antioch to Bibars, and when he died in 1275 he was only count of Tripoli.