Colos'se. More properly Colos'sae, was a city of Phrygia in Asia Minor, in the upper part of the basin of the Maeander, on the Lycus. Hierapolis and Laodicea were in its immediate neighborhood. Colossians 1:2; Colossians 4:13; Colossians 4:15-16. See Revelation 1:11; Revelation 3:14. St. Paul is supposed, by some, to have visited Colosse and founded or confirmed the Colossian church, on his third missionary journey. Acts 18:23; Acts 19:1.